Drinking about two glasses of wine or beer per day reduced a person's risk of premature death by 18%, compared with an 11% reduction for daily exercise, researchers reported at the American Association for the Advancement of Science's annual conference. Two cups of coffee per day reduced the risk of premature death by 10%.
The CDC's Advisory Committee on Immunization Practices recommended the use of AstraZeneca's FluMist Quadrivalent live attenuated influenza vaccine for the 2018-19 flu season, reversing its 2016 and 2017 announcements that the product was ineffective after seeing data demonstrating improved efficacy. The latest version uses a different type of influenza A H1N1 virus than the 2015-16 formulation, and providers may offer it as well as the inactivated influenza vaccine or the recombinant influenza vaccine for the upcoming season, CDC spokeswoman Kristen Nordlund says.
A study from Avalere Health found that 11 states plus the District of Columbia lack enough health care providers authorized to prescribe buprenorphine, which is used as part of opioid addiction treatment. The report compared opioid mortality rates from 2016 with the number of certified providers, finding that the national average was 1.6 opioid overdoses per authorized prescriber, but ratios were far less favorable in Iowa, Illinois, Maryland, Michigan, Missouri, New Hampshire, North Carolina, Ohio, Virginia, West Virginia and Wisconsin, as well as Washington, D.C.
The FDA is recalling and destroying kratom-containing dietary supplements distributed under the brand names Botany Bay, Divinity and Enhance Your Life. The agency has received reports of 36 deaths associated with the kratom plant, while CDC has reported 28 people in 20 states who have been infected with salmonella, and the outbreak has been linked to products that contain kratom.
Researchers evaluated data from 44,828 Chinese adults with impaired fasting glucose, ages 20 to 80, and found that those who engaged in high-volume physical activity reduced their risk of developing type 2 diabetes by 25% over 18 years, while those who engaged in low and moderate physical activity experienced a 12% and 20% diabetes risk reduction, respectively, compared with inactive individuals. The findings in the British Journal of Sports Medicine showed that 19.2% of type 2 diabetes cases could have been prevented if the participants engaged in the recommended amount of weekly exercise of at least 150 minutes.
Eight of the 13 cases of SGLT2 inhibitor-associated diabetic ketoacidosis were among adults with type 2 diabetes and five among patients with type 1 diabetes, with dapagliflozin and empagliflozin implicated in nine and four cases, respectively, according to a study in Diabetes Care. Researchers analyzed 85,851 empagliflozin and dapagliflozin prescriptions written in South Australia from December 2015 to March 2017 and found that, in a second analysis of 82 unique adverse event reports of SGLT2 inhibitor-associated DKA, 16 cases were classified as life-threatening and 18 cases required intensive care.
Researchers found a positive association between perioperative glucose and 1.0% 30-day mortality at mean glucose of 100 mg/dL and 1.6% at mean glucose of 200 mg/dL in noncardiac surgery, while perioperative glucose and 30-day mortality had a strong U-shaped relationship in cardiac surgery, with 4.5% mortality at 100 mg/dL, 1.5% at 140 mg/dL and 6.9% at 200 mg/dL. The findings in Diabetes Care, based on 13,077 cardiac and noncardiac surgeries, revealed no association between A1C and 30-day mortality in either cardiac or noncardiac procedures when controlling for blood glucose.
A study in the Journal of Diabetes showed that adults in the top quartile for non-HDL cholesterol/HDL cholesterol ratio had a 40% increased risk for type 2 diabetes, a mean of 0.1% higher A1C, a mean of 0.2 mmol/L fasting plasma glucose and a mean of 0.5 mmol/L higher 2-hour glucose level, compared with those in the lowest quartile for cholesterol ratio. Chinese researchers used a cohort of 4,882 individuals, ages at least 40, and found an association between each standard deviation increase in log transformed non-HDL cholesterol/HDL cholesterol ratio and a 10% increased diabetes risk, a 0.1 mmol/L higher FPG and a 0.2 mmol/L higher 2-hour glucose level.
Women in health care face obstacles to reporting inappropriate behavior and sexual harassment. "I think once we understand what the true definition of sexual harassment is, which is any advances that are unwelcome or unsolicited that are sexual, and we stop excusing it, then the change will happen. We want to drive accountability so we're able to enforce consequences," said Seun Ross, ANA's director of nursing practice and work environment.
L.A. Care Health Plan, which serves more than 2 million members in the Los Angeles, Calif., area, worked with the California Long-Term Care Education Center to launch a pilot program to train and educate in-home supportive services caregivers on proper care for dual-eligible beneficiaries. The 10-week course covers CPR, personal care, first aid and other skills, but the ultimate goal is training caregivers to notice and report small changes in members' functional status that could signal a bigger health problem.
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